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Sam-E 200Mg 60tab
Sam-E 200Mg 60tab
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Sam-E 200Mg 60tab

Natural Factors
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200 mg

  • Salt Free
  • Soy Free
  • Egg Free
  • Non GMO
  • Corn Free
  • Dairy Free
  • Vegetarian
  • Sugar Free
  • Starch Free
  • Wheat Free
  • Gluten Free
  • Tree Nuts Free
  • Made In Canada
  • Fish & Shellfish Free
  • Support for arthritic disorders
  • No artificial colours, preservatives, or sweeteners
  • Without the side effects of prescription antidepressants
  • Helps promote bile flow and inactivate excess estrogens
  • Helps raise serotonin, dopamine, and phosphatidylserine levels

SAMe (pronounced "sammy") is short for S-adenosyl-L-methionine or S-adenosyl-methionine, a natural molecule formed in the body by methionine and adenosyl-triphosphate (ATP). Supplemental SAMe helps to raise serotonin, dopamine, and phosphatidylserine levels.


Supplement Facts

Each Tablet Contains

Medicinal Ingredients Amount Per Serving
S-Adenosyl-L-Methionine (SAMe)  (from 400 mg of S-Adenosyl-L-Methionine Disulfate Tosylate) 200 mg


Non-Medicinal Ingredients

Microcrystalline cellulose, mannitol, enteric coating (methacrylic acid copolymer, talc, triethyl citrate, glyceryl palmitostearate, silica, titanium dioxide, medium chain triglycerides, yellow iron oxide), glyceryl behenate, vegetable grade magnesium stearate (lubricant), silica, sodium starch glycolate.


Recommended Dose

SAMe should always be taken on an empty stomach.

For Mood Balance

1–4 tablets 2 times daily or as directed by a health care practitioner.

For Osteoarthritic Pain

1–3 tablets 2 times daily or as directed by a health care practitioner.

Do not exceed a total of 8 tablets daily.

SAMe must be taken for a minimum of 2 weeks, at which time effects should be observed.

Recommended Use

Helps support healthy mood balance and relieve osteoarthritic pain.


If you are taking anti-depressant medications, consult a health care practitioner prior to taking SAMe in place of or in addition to those medications. Not recommended for use in children. Do not use if you are pregnant or breastfeeding. Do not take at night as SAMe may cause anxiety, restlessness, and insomnia. People with bipolar disorder (manic-depressive illness) should not use SAMe unless under medical supervision. Possible side effects are: mild gastrointestinal upsets (such as stomach pain, nausea, diarrhea, and flatulence), anxiety, hyperactive muscle movement, insomnia, and hypomania. When these side effects occur, they often diminish with time or resolve with lower doses or cessation of use. There are no documented cases of allergies to SAMe. Keep out of the reach of children.

Allergen Statement

Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, soy, corn, egg, fish, shellfish, salt, tree nuts, or GMOs. Suitable for vegetarians.